selective myd88 inhibitor Search Results


selective myd88 inhibitor  (MedChemExpress)
95
MedChemExpress selective myd88 inhibitor
TTFields-induced iNOS expression and cytokine secretion in polarized macrophages. BMDMs were polarized with IFN-γ or IL-4 and then exposed to TTFields with or without pharmacological in-hibitors, or LPS. iNOS protein expression was assessed by flow cytometry. ( A , B ) Comparison of iNOS levels in IFN-γ–primed macrophages treated with TTFields or LPS, and the effect of <t>MyD88</t> inhibition <t>(TJ-M2010-5)</t> or ROCK inhibition (Y-27632). ( C – E ) Western blot analysis of GEF-H1 and NF-κB p65 activation in IFN-γ–primed macrophages exposed to TTFields. ( F ) Cytokine and chemokine secretion profile measured by multiplex analysis in supernatants from IFN-γ–primed BMDMs. mean ± SEM; N = 3. * p < 0.05, ** p < 0.01, and *** p < 0.001; Student’s t -test.
Selective Myd88 Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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simple-western-system-0  (Bio-Techne corporation)
99
Bio-Techne corporation simple-western-system-0
TTFields-induced iNOS expression and cytokine secretion in polarized macrophages. BMDMs were polarized with IFN-γ or IL-4 and then exposed to TTFields with or without pharmacological in-hibitors, or LPS. iNOS protein expression was assessed by flow cytometry. ( A , B ) Comparison of iNOS levels in IFN-γ–primed macrophages treated with TTFields or LPS, and the effect of <t>MyD88</t> inhibition <t>(TJ-M2010-5)</t> or ROCK inhibition (Y-27632). ( C – E ) Western blot analysis of GEF-H1 and NF-κB p65 activation in IFN-γ–primed macrophages exposed to TTFields. ( F ) Cytokine and chemokine secretion profile measured by multiplex analysis in supernatants from IFN-γ–primed BMDMs. mean ± SEM; N = 3. * p < 0.05, ** p < 0.01, and *** p < 0.001; Student’s t -test.
Simple Western System 0, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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simple-western-system-0 - by Bioz Stars, 2026-04
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myd88 inhibitory peptide  (Novus Biologicals)
90
Novus Biologicals myd88 inhibitory peptide
TTFields-induced iNOS expression and cytokine secretion in polarized macrophages. BMDMs were polarized with IFN-γ or IL-4 and then exposed to TTFields with or without pharmacological in-hibitors, or LPS. iNOS protein expression was assessed by flow cytometry. ( A , B ) Comparison of iNOS levels in IFN-γ–primed macrophages treated with TTFields or LPS, and the effect of <t>MyD88</t> inhibition <t>(TJ-M2010-5)</t> or ROCK inhibition (Y-27632). ( C – E ) Western blot analysis of GEF-H1 and NF-κB p65 activation in IFN-γ–primed macrophages exposed to TTFields. ( F ) Cytokine and chemokine secretion profile measured by multiplex analysis in supernatants from IFN-γ–primed BMDMs. mean ± SEM; N = 3. * p < 0.05, ** p < 0.01, and *** p < 0.001; Student’s t -test.
Myd88 Inhibitory Peptide, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
myd88 inhibitory peptide - by Bioz Stars, 2026-04
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nci myd88 oci ly3 abc dlbcl louis staudt  (DSMZ)
95
DSMZ nci myd88 oci ly3 abc dlbcl louis staudt
TTFields-induced iNOS expression and cytokine secretion in polarized macrophages. BMDMs were polarized with IFN-γ or IL-4 and then exposed to TTFields with or without pharmacological in-hibitors, or LPS. iNOS protein expression was assessed by flow cytometry. ( A , B ) Comparison of iNOS levels in IFN-γ–primed macrophages treated with TTFields or LPS, and the effect of <t>MyD88</t> inhibition <t>(TJ-M2010-5)</t> or ROCK inhibition (Y-27632). ( C – E ) Western blot analysis of GEF-H1 and NF-κB p65 activation in IFN-γ–primed macrophages exposed to TTFields. ( F ) Cytokine and chemokine secretion profile measured by multiplex analysis in supernatants from IFN-γ–primed BMDMs. mean ± SEM; N = 3. * p < 0.05, ** p < 0.01, and *** p < 0.001; Student’s t -test.
Nci Myd88 Oci Ly3 Abc Dlbcl Louis Staudt, supplied by DSMZ, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nci myd88 oci ly3 abc dlbcl louis staudt/product/DSMZ
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004-700  (Bio-Techne corporation)
94
Bio-Techne corporation 004-700
TTFields-induced iNOS expression and cytokine secretion in polarized macrophages. BMDMs were polarized with IFN-γ or IL-4 and then exposed to TTFields with or without pharmacological in-hibitors, or LPS. iNOS protein expression was assessed by flow cytometry. ( A , B ) Comparison of iNOS levels in IFN-γ–primed macrophages treated with TTFields or LPS, and the effect of <t>MyD88</t> inhibition <t>(TJ-M2010-5)</t> or ROCK inhibition (Y-27632). ( C – E ) Western blot analysis of GEF-H1 and NF-κB p65 activation in IFN-γ–primed macrophages exposed to TTFields. ( F ) Cytokine and chemokine secretion profile measured by multiplex analysis in supernatants from IFN-γ–primed BMDMs. mean ± SEM; N = 3. * p < 0.05, ** p < 0.01, and *** p < 0.001; Student’s t -test.
004 700, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/004-700/product/Bio-Techne corporation
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004-700 - by Bioz Stars, 2026-04
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Image Search Results


TTFields-induced iNOS expression and cytokine secretion in polarized macrophages. BMDMs were polarized with IFN-γ or IL-4 and then exposed to TTFields with or without pharmacological in-hibitors, or LPS. iNOS protein expression was assessed by flow cytometry. ( A , B ) Comparison of iNOS levels in IFN-γ–primed macrophages treated with TTFields or LPS, and the effect of MyD88 inhibition (TJ-M2010-5) or ROCK inhibition (Y-27632). ( C – E ) Western blot analysis of GEF-H1 and NF-κB p65 activation in IFN-γ–primed macrophages exposed to TTFields. ( F ) Cytokine and chemokine secretion profile measured by multiplex analysis in supernatants from IFN-γ–primed BMDMs. mean ± SEM; N = 3. * p < 0.05, ** p < 0.01, and *** p < 0.001; Student’s t -test.

Journal: International Journal of Molecular Sciences

Article Title: Pro-Inflammatory Macrophage Phenotype Skewing Induced by Tumor Treating Fields (TTFields)

doi: 10.3390/ijms262412086

Figure Lengend Snippet: TTFields-induced iNOS expression and cytokine secretion in polarized macrophages. BMDMs were polarized with IFN-γ or IL-4 and then exposed to TTFields with or without pharmacological in-hibitors, or LPS. iNOS protein expression was assessed by flow cytometry. ( A , B ) Comparison of iNOS levels in IFN-γ–primed macrophages treated with TTFields or LPS, and the effect of MyD88 inhibition (TJ-M2010-5) or ROCK inhibition (Y-27632). ( C – E ) Western blot analysis of GEF-H1 and NF-κB p65 activation in IFN-γ–primed macrophages exposed to TTFields. ( F ) Cytokine and chemokine secretion profile measured by multiplex analysis in supernatants from IFN-γ–primed BMDMs. mean ± SEM; N = 3. * p < 0.05, ** p < 0.01, and *** p < 0.001; Student’s t -test.

Article Snippet: Specific inhibitors were added to probe the mechanism of TTFields action: a selective MyD88 inhibitor (10 μM; TJ-M2010-5, MedChemExpress, NJ, USA; Cat# HY-139397) or a Rho-associated kinase (ROCK) inhibitor (15 μM, Y-27632, Cayman Chemical, MI, USA; Cat# 10005583) were added immediately before TTFields exposure and maintained during it.

Techniques: Expressing, Flow Cytometry, Comparison, Inhibition, Western Blot, Activation Assay, Multiplex Assay